. Author manuscript; available in PMC: 2014 Dec 15.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Mar 18;23(6):1018–1024. doi: 10.1158/1055-9965.EPI-13-0635-T

Table 3.

BRCA1 and BRCA2 mutation carrier status and mean telomere length In all study individuals.

Differences in telomere length (δΔCt) between BRCA mutation carriers and non-carrier relatives in each study are shown. Associations are presented as β-coefficients with 95% confidence intervals (95%CI). Estimates are shown for all non-carriers compared to all carriers. Analyses are adjusted for age, study plate, relatedness and gender.

	Telomere length and carrier status β-coeff (95%CI)
Relative telomere length	All Carriers 3134 carriers, 1688 non-carriers	BRCA1 mutation carriers 1628 carriers, 1688 non-carriers	BRCA2 mutation carriers 1506 carriers, 1688 non-carriers
All non-carriers	0.00 ref	0.00 ref	0.00 ref
All carriers	−0.056 (−0.091 to -0.021)	−0.038 (−0.079 to 0.003)	−0.067 (−0.108 to −0.026)
P-value	0.0018	0.068	0.0016