Table 1. Median (IQR) Clinical Characteristics among U.S. Military Personnel Injured in Combat (2009-2011) with Wound Cultures Showing Fungal Growth.
| Clinical Parameters | Wounds with Recurrent Necrosisa (N = 77) | Wounds without Recurrent Necrosis (N = 19) | p-value |
|---|---|---|---|
| In Theater Shock Indices (combat support hospital) | |||
| Heart Rate | 125 (103, 140) | 135 (110, 153) | 0.22 |
| Systolic blood pressure | 99 (80.0, 123) | 130 (103, 147) | 0.02 |
| Blood gas – base deficit | 9 (13, 4) | 5 (7, 3) | 0.07 |
| Blood gas – pH | 7.2 (7.1, 7.3) | 7.3 (7.3, 7.3) | 0.03 |
| Blood Product Requirements in Theater (1st 24 hours) | |||
| Packed red blood cells + whole blood | 30 (17, 42) | 25 (14, 33) | 0.16 |
| Fresh frozen plasma + whole blood | 29 (18, 40) | 27 (12, 31) | 0.07 |
| LRMC | |||
| Maximal WBC count (109 cells/L) | 11 (7, 14) | 11 (7, 12) | 0.88 |
| Maximal temperature (°C) | 39 (39, 40) | 39 (39, 39) | 0.47 |
| ISS | 21 (17, 26) | 21 (14, 21) | 0.22 |
| SOFA score | 7 (4, 10) | 5 (4, 7) | 0.05 |
| U.S. MTF | |||
| Maximal WBC count - 1st week (109 cells/L) | 22 (15, 31) | 15 (13, 20) | 0.01 |
| Maximal temperature - 1st week (°C) | 39 (39, 40) | 39 (39, 39) | 0.02 |
| Maximal WBC count - 2nd week (109 cells/L) | 27 (19, 34) | 15 (11, 24) | <0.01 |
| Maximal temperature - 2nd week (°C) | 39 (39, 39) | 38 (38, 39) | 0.01 |
| SOFA score | 5 (1, 8) | 3 (2, 4) | 0.28 |
IQR - Interquartile Range; ISS - Injury Severity Score; LRMC - Landstuhl Regional Medical Center; MTF - Military Treatment Facility; SOFA - Sequential Organ Failure Assessment; WBC - White Blood Cell
a
Patients met the invasive fungal wound infection case definition4