TABLE 4.
NK cell interactions affect virus-specific T cell responses through direct and indirect mechanisms
| Intercellular interaction |
NK cell receptor | TargeT cell ligand | Species | Outcome |
|---|---|---|---|---|
| NK-T cell | NKG2D | MICA, ULBP1–3 | Human | TargeT cell lysis |
| RAE-1, MULT-1 | Mouse | TargeT cell lysis | ||
| TRAIL | TRAIL-R1/R2 | Human | TargeT cell lysis | |
| NKG2A/CD94 | HLA-E | Human | Block lysis | |
| Qa-1b | Mouse | Block lysis | ||
| 2B4 | CD48 | Mouse | Block lysis | |
| NK-DC | NKp30 | BAT3 | Human | Activates DCs |
| NKG2D | ? | Mouse | Activates DCs | |
| DNAM-1 | Nectin-2, CD155 | Human, mouse |
DC lysis | |
| NKp30 | ? | Human | DC lysis | |
| NKG2A/CD94 | HLA-E | Human | Block lysis |