TABLE 4.
Intercellular interaction |
NK cell receptor | TargeT cell ligand | Species | Outcome |
---|---|---|---|---|
NK-T cell | NKG2D | MICA, ULBP1–3 | Human | TargeT cell lysis |
RAE-1, MULT-1 | Mouse | TargeT cell lysis | ||
TRAIL | TRAIL-R1/R2 | Human | TargeT cell lysis | |
NKG2A/CD94 | HLA-E | Human | Block lysis | |
Qa-1b | Mouse | Block lysis | ||
2B4 | CD48 | Mouse | Block lysis | |
NK-DC | NKp30 | BAT3 | Human | Activates DCs |
NKG2D | ? | Mouse | Activates DCs | |
DNAM-1 | Nectin-2, CD155 | Human, mouse |
DC lysis | |
NKp30 | ? | Human | DC lysis | |
NKG2A/CD94 | HLA-E | Human | Block lysis |