Fig. 1.

Comparative efficiency of antiviral drugs to reduce acute infection in induced pluripotent stem-derived neural progenitor cells (NPCs) and neurons. Top panel: microphotographs of NPCs and neuronal cultures infected with herpes simplex virus, type 1 (HSV-1) (multiplicity of infection of 0.1 and 0.3, respectively) in the presence or absence of viral replication inhibitors acyclovir or 5-(E)-5-(2-bromovinyl)-2′-deoxyuridine along with interferon-α. Bottom panel: fluorescence-activated cell sorting analysis of uninfected and HSV-1 infected NPC and neuronal cultures. Scale bar is 50 μm. For a color version, see this figure online.