Figure 2.
(A–C) Effect of BMP4 and Noggin, alone (A, B) or in combination (C), on numbers of IVD-oocytes formed per well of 2.5 × 104 OSCs after 16 hours of treatment (mean ± SEM, n = 3–4 independent cultures; different letters, P < 0.05). (D) Lack of effect of BMP4 (100 ng/mL) and Noggin (150 ng/mL), alone or in combination, on proliferation of OSCs (2.5 × 104 cells initially seeded per well) over a 40-hour culture period (mean ± SEM, n = 4 independent cultures; no significant differences detected).
