TABLE III.

Association Between Quality-of-Life Scores and Clinical Variables.

		Detected Primary	Occult Primary	P Value	TORS + RT	TORS + CRT	P Value	HPV+	HPV−	P Value
Speech	Baseline	94	86	.831	88	95	.497	92	89	.079
	3 weeks	85	76	.314	80	85	.640	81	92	.311
	3 months	72	41	.060	65	69	.784	64	85	.226
	6 months	79	73	.638	77	78	.921	75	89	.290
	12 months	88	93	.675	86	91	.631	88	—	*
Eating	Baseline	95	82	.046†	87	95	.178	91	93	.897
	3 weeks	75	58	.112	71	70	.921	73	70	.767
	3 months	47	32	.244	43	45	.863	44	51	.628
	6 months	59	41	.170	49	61	.259	53	72	.469
	12 months	67	69	.930	63	72	.607	67	—	*
Aesthetics	Baseline	97	73	.072	81	98	.113	88	94	.959
	3 weeks	89	58	.075	72	88	.573	79	91	.474
	3 months	72	17	.008†	64	59	.790	64	67	.896
	6 months	83	67	.252	84	75	.452	79	83	.766
	12 months	81	69	.527	81	75	.718	78	—	*
Social disruption	Baseline	97	81	.036†	92	92	.278	92	90	.327
	3 weeks	73	65	.458	76	65	.204	72	67	.646
	3 months	64	39	.209	65	53	.467	67	40	.184
	6 months	82	79	.775	84	79	.209	84	81	.807
	12 months	90	95	.720	98	84	.181	91	—	*
Overall QOL	Baseline	85	79	.579	78	88	.315	94	75	.442
	3 weeks	81	80	.945	78	83	.662	79	88	.484
	3 months	52	42	.614	50	50	1.0	48	58	.625
	6 months	66	75	.677	68	68	1.0	63	83	.358
	12 months	92	75	.315	94	81	.390	88	—	*

HPV⁺ means positive for high-risk types of human papillomavirus; HPV⁻ means negative for high-risk types of human papillomavirus.

^*No statistics were computed because of absent data.

^†Statistically significant (P <.05).

CRT = chemoradiation therapy; HPV = human papillomavirus; QOL = quality of life; RT = radiotherapy; TORS = transoral robotic surgery.