Figure 9.

Percent of reduction of tumor burden in a cohort of 12 female NOD.CB17-Prkdc scid/J mice inoculated subcutaneously with 5 × 10⁶ MDA-MB-231 cells. The treatment started when tumors were palpable (5–6 mm diameter). Six mice were treated with compound 2 (pink bars), six were treated with the vehicle 100 μL of normal saline (0.9% NaCl) (black bars). 2 was administered in the amount of 5 mg/kg/every other day.