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. 2014 Nov 10;57(23):10176–10191. doi: 10.1021/jm501578n

Table 3. Heterocycle Modifications.

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a

LLE is calculated using LogD measured at pH 7.4.

b

Ki data are an average of at least two independent experiments.

c

Ratio of wtEGFR Kiapp over EGFR(TMLR) Kiapp.

d

Ratio of wtEGFR Kiapp over EGFR(TMdel) Kiapp.