. 2014 Dec 8;20:2578–2583. doi: 10.12659/MSM.892374

Table 4.

Association between C1772T polymorphism and clinico-pathological parameters and habits of the breast cancer patients based on the dominant models.

Clinic index	Genotype (N)		Association		Heterogeneity test

	CC	CT+TT	OR (95% CI)	P	I²	df	P
Menopausal status
Premenopausal	93	21	0.72(0.38–1.34)	0.30	0	2	0.50
Postmenopausal	121	38	0.72(0.38–1.34)	0.30	0	2	0.50

Clinical stage
I	502	61	1.01(0.69–1.48)	0.97	0	1	0.34
II+III	472	59	1.01(0.69–1.48)	0.97	0	1	0.34

Lymph nodes
Negative	767	131	1.15(0.86–1.53)	0.35	51	3	0.10
Positive	567	107	1.15(0.86–1.53)	0.35	51	3	0.10

Histological grade
I+II	237	68	0.69(0.46–1.05)	0.08	45	2	0.16
III	164	60	0.69(0.46–1.05)	0.08	45	2	0.16

ER status
Negative	491	95	1.10(0.81–1.50)	0.52	0	2	0.62
Positive	735	116	1.10(0.81–1.50)	0.52	0	2	0.62

Cigarette smoking
Yes	15	9	2.24(0.90–5.55)	0.08	0	1	0.95
No	131	35	2.24(0.90–5.55)	0.08	0	1	0.95

Alcohol intake
Yes	17	8	1.81(0.69–4.76)	0.23	0	1	0.45
No	129	35	1.81(0.69–4.76)	0.23	0	1	0.45