Figure 2.

Colocalization of MRP1 and Cav-1 in the three cell lines.

Notes: (A–C) PNT2, (D–F) LNCaP, and (G–I) PC3 using confocal microscopy. MRP1 and Cav-1 colocalized in CaP cells in some regions of the plasma membrane and in cytoplasmic accumulations (F and I). A few colocalizations were found in the plasma membrane of normal prostate cells (C).

Abbreviations: MRP1, multidrug resistance protein 1; Cav-1, Caveolin-1; CaP, prostate cancer; PNT2, normal human prostatic epithelial cell line; LNCaP, lymph node carcinoma of the prostate; PC3, prostate cancer cell 3 line.