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. 2014 Dec 5;7:2215–2225. doi: 10.2147/OTT.S69530

Table 1.

Counting of caveolae in the surface of the plasma membrane of the three prostate cell lines: PNT2 (normal), LNCaP (androgen-sensitive), and PC3 (androgen-independent)

Cell type Perimeter of analyzed membrane surface (μm) Number of caveolae Ratio (caveolae/perimeter)
PNT2 213.63a 45.66±4.00 0.21±0.02
LNCaP 325.62b 145.66±5.50 0.45±0.02
PC3 294.67c 103.33±2.52 0.35±0.01

Notes: Different sections of ten cells were counted (n=3 times from the same sample) for caveolae, and the ratio of the number of caveolae per perimeter of analyzed surface was obtained. Prostate cancer cell lines have approximately double the number of caveolae that normal prostate cells do.

a

P<0.001 PNT2 compared with LNCaP

b

P=0.033 PNT2 compared with PC3

c

ns P=0.123 LNCaP compared with PC3.

Abbreviations: PNT2, normal human prostatic epithelial cell line; LNCaP, lymph node carcinoma of the prostate; PC3, prostate cancer cell 3 line; ns, not significant.