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. Author manuscript; available in PMC: 2014 Dec 15.
Published in final edited form as: Microb Pathog. 2011 Jul 5;51(4):233–242. doi: 10.1016/j.micpath.2011.06.006

Fig. 10.

Fig. 10

Induction of the macrophage respiratory burst by WGP is mediated by Dectin-1. The experiment was performed as described in the legend of Fig. 7, except that MDM monolayers were pre-treated with anti-Dectin-1 or isotype control antibody before the addition of DCF followed by WGP. Graphs show the mean values of RFUs from triplicate wells from a representative experiment (n = 2). A) RFU profile over 90 min period obtained from MDMs pre-treated with anti-dectin-1 or isotype control antibody and stimulated with WGP or media control. B) Bar graph shows the end-point ROI values at 90 min plotted from mean RFUs in graph A. Antibody blocking of Dectin-1 significantly reduced ROI production in response to WGP (*p < 0.05; **p < 0.005).