Table 2.
Allelic, genotypic and haplotypic frequencies of 1513A>C and 489C>T polymorphisms in the control and AD groups.
| Control | AD | p | |
|---|---|---|---|
| Alleles n (%) | |||
| 1513A>C | |||
| A | 220 (74) | 128 (76) | 0.74a |
| C | 76 (26) | 40 (24) | |
| Total | 296 | 168 | |
| 489C>T | |||
| C | 130 (44) | 98 (58) | 0.0037a |
| T | 166 (56) | 70 (42) | |
| Total | 296 | 168 | |
| Genotypes n (%) | |||
| 1513A>C | |||
| AA | 83 (55) | 52 (62) | 0.45b |
| AC | 54 (36) | 24 (29) | |
| CC | 11 (7) | 8 (9) | |
| Total | 148 | 84 | |
| 489C>T | |||
| CC | 30 (20) | 27 (32) | 0.01b |
| CT | 70 (47) | 44 (52) | |
| TT | 48 (33) | 13 (16) | |
| Total | 148 | 84 | |
| Haplotypes n (%) | |||
| A/C | 113 (38) | 76 (45) | 0.0022b |
| A/T | 107 (36) | 52 (31) | |
| C/T | 59 (20) | 18 (11) | |
| C/C | 17 (6) | 22 (13) | |
| Total | 296 | 168 |
Bold entries indicate a significant p value.
a
Fisher exact test.
b
Chi-square test.