Table 1.
Parameter | Males Hjv−/− | Females Hjv−/− | Sex Difference T-Test Hjv−/− | Males wild type | Females wild type | Sex Difference T-Test wild type |
---|---|---|---|---|---|---|
Heart Iron (μg/g wet weight) | 238 ± 73 | 163 ± 29 | < 0.0001 | 79 ± 7 | 82 ± 7 | < 0.40 |
Heart Weight (g) | 0.147 ± 0.026 | 0.131 ± 0.020 | < 0.01 | 0.153 ± 0.012 | 0.128 ± 0.014 | < 0.01 |
Liver Iron (μg/g wet weight) | 2041 ± 492 | 1776 ± 527 | < 0.05 | 237 ± 50 | 317 ± 55 | < 0.05 |
Liver Weight (g) | 1.49 ± 0.26 | 1.42 ± 0.29 | < 0.30 | 1.09 ± 0.09 | 0.94 ± 0.15 | < 0.08 |
Hamp1 (relative to β-actin) | 1.6 ± 1.2 | 2.5 ± 1.3 | < 0.19 | 26 ± 1 | 32 ±1 | < 0.23 |
Body Weight (g) | 26 ± 3 | 24 ± 2 | < 0.05 | 28 ± 2 | 22 ± 1 | < 0.0001 |
Geometric mean ± standard deviation is displayed for Hamp1; all other values are arithmetic mean ± standard deviation. Calculations for Hjv −/− mice include the data from all five Hjv−/− male groups (M-intact, OrchX+T, OrchX+E, OrchX+DHT, OrchX) and all three Hjv −/− female groups (F-intact, OVX, OVX+E).