Table 1.
Effects of fish oil on WAT gene expression after 9 months of supplementation in 6T and B6.
| B6 | 6T | P Genotype | P Diet | P Int | |||
|---|---|---|---|---|---|---|---|
| Gene | Safflower | Fish | Safflower | Fish | |||
| Leptin | 1.00±0.13 | 0.58±0.08** | 0.69±0.13 | 0.59±0.12 | NS | 0.03 | NS |
| AdipoQ | 1.00±0.10 | 0.58±0.09** | 0.54±0.10 | 0.51±0.19 | 0.05 | 0.08 | NS |
| Pparβ | 1.00±0.19 | 2.58±0.73* | 1.91±0.67 | 1.92±0.45 | NS | NS | NS |
| Tnfα | 1.00±0.23 | 1.59±0.27 | 2.68±0.67 | 4.04±0.67$ | 0.006 | 0.01 | NS |
| Pparγ | 1.00±0.44 | 0.16±0.05 | 0.55±0.28 | 0.84±0.74 | NS | NS | NS |
| Fas | 1.00±0.10 | 0.63±0.17 | 0.90±0.17 | 1.68±0.39* | 0.05 | NS | 0.02 |
| Lpl | 1.00±0.14 | 0.96±0.11 | 1.91±0.59 | 1.29±0.30 | 0.05 | NS | NS |
| Srebp | 1.00±0.14 | 1.94±0.75 | 1.63±0.65 | 2.58±1.07 | NS | NS | NS |
Gene expression was evaluated by qRTPCR (n=6–8 per group).
p<0.05 significant difference vs safflower in each genotype;
p<0.05 significant difference vs B6 in each diet by post-hoc fisher’s PLSD (2F-ANOVA, genotype and diet). Interaction, Int. Means ± SEM.