Table 1. Associations of observed confounders with ADH1B and ADH1C genotype.
| ADH1B | ADH1C | ||||||
| Mean (SD) or N (%) by genotype | Mean (SD) or N (%) by genotype | ||||||
| 1/1 (slow)N = 55,880 | 1/2 or 2/2(fast) N = 2433 | p-valuea | 2/2 (slow)N = 10,155 | 1/2 (intermediate)N = 28,415 | 1/1 (fast)N = 19,743 | p-valuea | |
| Age (years) | 56.6 (13.4) | 57.1 (13.3) | 0.13 | 56.6 (13.3) | 56.7 (13.3) | 56.6 (13.4) | 0.55 |
| Women (n, %) | 31,144 (56) | 1,324 (54) | 0.20 | 5,741 (56) | 15,818 (56) | 10,909 (55) | 0.11 |
| Current smoker (n, %) | 11,813 (21) | 514 (21) | 0.99 | 2,221 (22) | 5,957 (21) | 4,149 (21) | 0.14 |
| >4 hours per week MVPA | 26,871 (48) | 1,194 (49) | 0.34 | 4,898 (48) | 13,662(48) | 9,505 (48) | 0.96 |
| Income >600,000Kr | 10,767 (19) | 499 (20) | 0.13 | 1,946 (19) | 5,535 (19) | 3,785 (19) | 0.64 |
| Education >13 years | 9,425(17) | 416 (17) | 0.76 | 1,776 (17) | 4,738 (17) | 3,327 (17) | 0.17 |
N = 58,313.
a
F-statistic for continuous variables and chi-square for categorical variables testing the null hypothesis that distributions of the confounders do not differ by genotype (1 degree of freedom for ADH1B and 2 degrees of freedom for ADH1C).
MVPA = Moderate or vigorous physical activity. Kr = Danish kroner.