Table 2. The association of TL (kbp) with different parameters of cardiovascular function using general linear models.
Response variable (RV) | Model 1 | Model 2 | Model 3 | |
E/A | b | 0.0696 | 0.0249 | 0.0264 |
P | 2.83E-16 | 1.25E-03 | 8.09E-05 | |
e′/a′ | b | 0.0764 | 0.0178 | 0.0182 |
P | <2.2e-16 | 0.0281 | 0.0120 | |
E (cm/s) | b | 1.91 | 0.195 | 0.226 |
P | 1.09E-06 | 0.600 | 0.535 | |
A (cm/s) | b | −1.60 | −0.860 | −0.905 |
P | 5.37E-07 | 4.62E-03 | 4.51E-04 | |
e′ (cm/s) | b | 0.397 | 0.050 | 0.043 |
P | 8.93E-13 | 0.304 | 0.341 | |
a′ (cm/s) | b | −0.211 | −0.068 | −0.079 |
P | 5.77E-07 | 0.100 | 0.0403 | |
E/e′ | b | −0.158 | −0.0214 | −0.0124 |
P | 2.62E-3 | 0.677 | 0.794 | |
DT (ms) | b | −1.86 | −0.123 | −0.302 |
P | 2.24E-02 | 0.881 | 0.712 | |
IVRT (s) | b | −2.70 | −0.941 | −0.900 |
P | 2.32E-12 | 9.25E-03 | 0.0115 | |
log(NTproBNP (pg/ml)) | b | 0.017 | −0.004 | −0.005 |
P | 0.119 | 0.657 | 0.617 | |
LVM index (g/m1.7) | b | −2.37 | −0.194 | 0.0228 |
P | 5.41E-08 | 0.616 | 0.943 | |
LVEDD (mm) | b | −0.497 | −0.164 | −0.124 |
P | 1.11E-04 | 0.158 | 0.261 | |
EF (%) | b | 0.0216 | −0,0183 | 0.0156 |
P | 0.906 | 0.922 | 0.933 | |
s′ (cm/s) | b | 0.018 | −0.033 | −0.038 |
P | 0.579 | 0.315 | 0.238 |
Model 1: RV ∼ TL.
Model 2: RV ∼ TL+Age+Sex.
Model 3: Model 2+Systolic BP+Heart Rate+BMI+Used Antihypertensive Drugs.
E & A: peak transmitral flow velocities during early (E) and late (A) diastolic filling, e′ & a′: peak movement speed of mitral annulus during early (e′) and late (a′) diastolic filling, DT: transmitral Deceleration Time, IVRT: Isovolumic Relaxation Time, NTproBNP: N-terminal prohormone of brain natriuretic peptide, LVM: allometrically scaled Left Ventricular Mass index, LVEDD: Left Ventricular End-Diastolic Diameter, EF: Ejected Fraction of end-diastolic volume, s′: peak systolic mitral annulus movement speed, b: effect size (unstandardized), P: P-value of TL component.