Table 2. The association of TL (kbp) with different parameters of cardiovascular function using general linear models.

Response variable (RV)		Model 1	Model 2	Model 3
E/A	b	0.0696	0.0249	0.0264
	P	2.83E-16	1.25E-03	8.09E-05
e′/a′	b	0.0764	0.0178	0.0182
	P	<2.2e-16	0.0281	0.0120
E (cm/s)	b	1.91	0.195	0.226
	P	1.09E-06	0.600	0.535
A (cm/s)	b	−1.60	−0.860	−0.905
	P	5.37E-07	4.62E-03	4.51E-04
e′ (cm/s)	b	0.397	0.050	0.043
	P	8.93E-13	0.304	0.341
a′ (cm/s)	b	−0.211	−0.068	−0.079
	P	5.77E-07	0.100	0.0403
E/e′	b	−0.158	−0.0214	−0.0124
	P	2.62E-3	0.677	0.794
DT (ms)	b	−1.86	−0.123	−0.302
	P	2.24E-02	0.881	0.712
IVRT (s)	b	−2.70	−0.941	−0.900
	P	2.32E-12	9.25E-03	0.0115
log(NTproBNP (pg/ml))	b	0.017	−0.004	−0.005
	P	0.119	0.657	0.617
LVM index (g/m1.7)	b	−2.37	−0.194	0.0228
	P	5.41E-08	0.616	0.943
LVEDD (mm)	b	−0.497	−0.164	−0.124
	P	1.11E-04	0.158	0.261
EF (%)	b	0.0216	−0,0183	0.0156
	P	0.906	0.922	0.933
s′ (cm/s)	b	0.018	−0.033	−0.038
	P	0.579	0.315	0.238

Model 1: RV ∼ TL.

Model 2: RV ∼ TL+Age+Sex.

Model 3: Model 2+Systolic BP+Heart Rate+BMI+Used Antihypertensive Drugs.

E & A: peak transmitral flow velocities during early (E) and late (A) diastolic filling, e′ & a′: peak movement speed of mitral annulus during early (e′) and late (a′) diastolic filling, DT: transmitral Deceleration Time, IVRT: Isovolumic Relaxation Time, NTproBNP: N-terminal prohormone of brain natriuretic peptide, LVM: allometrically scaled Left Ventricular Mass index, LVEDD: Left Ventricular End-Diastolic Diameter, EF: Ejected Fraction of end-diastolic volume, s′: peak systolic mitral annulus movement speed, b: effect size (unstandardized), P: P-value of TL component.