Figure 2. Effect of high-fat diet plus olanzapine (OLZ; filled circles) versus placebo (PLA; open circles) on body weight in germ-free mice.

Points in the left-hand third represent observations under germ-free conditions. The first dashed line marks the beginning of the drug-free conventionalization period (with colonization by gavage) and the second dashed line marks the resumption of treatment under conventional conditions. Each point represents the mean across 12 mice; error bars are ± 2 standard error.