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. 2014 Dec 15;9(12):e115377. doi: 10.1371/journal.pone.0115377

Table 4. Multivariable* hazard ratio (95% CI) of AHEI-2010 components (per serving per day unless otherwise specified) for mortality in NHS (1986–2010).

Components Overall mortality Colorectal cancer mortality
Red/processed meat 1.07 (0.87, 1.30) 1.22 (0.90, 1.67)
Nuts 0.98 (0.82, 1.17) 0.69 (0.49, 0.97)**
Sugar sweetened beverages + juices 1.11 (1.01, 1.23)** 1.16 (0.99, 1.35)
Whole grains 0.98 (0.95, 1.01) 0.97 (0.93, 1.02)
Vegetables 1.00 (0.94, 1.06) 0.94 (0.84, 1.04)
Whole fruits 1.08 (0.98, 1.20) 1.03 (0.87, 1.21)
Polyunsaturated to saturated fat ratio 0.98 (0.93, 1.03) 1.00 (0.93, 1.07)
Long chain omega-3 0.87 (0.53, 1.43) 0.63 (0.26, 1.54)
Sodium 1.00 (0.95, 1.05) 0.94 (0.86, 1.03)
Trans fat 0.97 (0.88, 1.07) 1.07 (0.92, 1.24)
Alcohol
No intake 1.30 (1.05, 1.61)** 1.32 (0.93, 1.87)
5–15 g/day 1 (ref) 1 (ref)
>15 g/day 1.22 (0.85, 1.76) 0.97 (0.50, 1.87)

*Adjusted for age, physical activity, BMI, weight change, cancer grade, chemotherapy, smoking status, energy intake, colon or rectal cancer, stage of disease, date of colorectal cancer diagnosis.

**After additional adjustment for an AHEI-2010 score without the specific component, RR of overall mortality for alcohol, sweetened beverages + juices remained unchanged and significant, but for nuts and CRC mortality was slightly attenuated and no longer significant (RR = 0.71, 95% CI = 0.50 = 1.01).