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. 2014 Nov 19;4(6):738–750.

Figure 5.

Figure 5

A. The relative expression of miR-199a-3p was detected by qRT-PCR in 33 cases of paraffin-embedded osteosarcoma tissues and paired normal muscle tissues. The expression of miR-199a-3p was clearly lower in tumors than in paired normal tissues; B. In those 33 cases studied, DFS and OS in the group with low miR-199a-3p expression were significantly lower than in group with high miR-199a-3p expression (P < 0.001); C. The relative expression of miR-199a-3p and AXL mRNAs were detected in 30 cases of fresh frozen osteosarcoma tissues and paired normal tissues. Consistent with the expression level in paraffin-embedded tissues, the expression of miR-199a-3p is clearly lower in tumor than in normal tissues, while the expression of AXL showed the opposite; D. A statistically significant negative correlation was found between miR-199a-3p and AXL in those 30 osteosarcoma cases by Pearson statistical analysis, r=-0.479, P < 0.01).