Table 5.
Cut-off score of Hsp90-beta serum level for differentiating lung cancer patients from normal and benign groups
| Selection of cut-off score for serum value of Hsp90-beta in lung cancer patients and healthy examined peoples | ||||
|
| ||||
| Criterion | Sensitivity | 95% CI | Specificity | 95% CI |
|
| ||||
| > 1.1058 | 100.00 | 95.5-100.0 | 73.81 | 63.1-82.8 |
| > 1.1438 | 98.77 | 93.3-100.0 | 78.57 | 68.3-86.8 |
| > 1.1552* | 98.77 | 93.3-100.0 | 83.33 | 73.6-90.6 |
| > 1.173 | 90.12 | 81.5-95.6 | 85.71 | 76.4-92.4 |
| > 1.212 | 87.65 | 78.5-93.9 | 92.86 | 85.1-97.3 |
| > 1.232 | 85.19 | 75.6-92.1 | 95.24 | 88.3-98.7 |
| > 1.2806 | 75.31 | 64.5-84.2 | 100.00 | 95.7-100.0 |
|
| ||||
| Selection of cut-off score for serum value of Hsp90-beta in lung cancer patients and benign lung disease patients | ||||
|
| ||||
| Criterion | Sensitivity | 95% CI | Specificity | 95% CI |
|
| ||||
| > 1.097 | 100.00 | 98.6-100.0 | 57.73 | 50.9-64.3 |
| > 1.12 | 98.51 | 96.2-99.6 | 57.73 | 50.9-64.3 |
| > 1.1331 | 98.51 | 96.2-99.6 | 67.27 | 60.6-73.4 |
| > 1.1578* | 95.90 | 92.8-97.9 | 72.27 | 65.9-78.1 |
| > 1.232 | 84.33 | 79.4-88.5 | 74.55 | 68.3-80.2 |
| > 1.2965 | 72.76 | 67.0-78.0 | 93.18 | 89.0-96.1 |
| > 1.3212 | 63.81 | 57.7-69.6 | 95.45 | 91.8-97.8 |
| > 1.3706 | 38.81 | 32.9-44.9 | 100.00 | 98.3-100.0 |
95% CI, 95% confidence;
threshold of serum annexin A1 for differentiating lung cancer patient from benign lung disease patient and normal people.