Table 1.
mTOR pathway: sensibility in detecting biomarkers by three tissue-based techniques
| 1 Molecules | Immunohistochemistry (IHC) | Western blot (WB) | Immunofluorescence (IF) |
|---|---|---|---|
| mTOR | - | - | ++ |
| p-mTOR | ++ | - | // |
| p70S6k | - | ++ | // |
| p-p70S6k monoclonal | ++ | - | + |
| p-p70S6k polyclonal | - | - | // |
| p-S6RP | - | ++ | // |
| p-4EBP1 | - | ++ | // |
//: not recommend.