Table 4.
Cox proportional hazard analysis of EP1-4 and pathological features in correlation to cancer-specific survival (CSS) and bladder-cancer recurrence in patients with NMIBC
| Recurrence-free survival univariate analysis | CSS univariate analysis | Recurrence-free survival multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| p | SE | HR (95% CI) | p | SE | HR (95% CI) | p | SE | HR (95% CI) | |
| EP1 (c) | 0.374 | 0.045 | 0.961 (0.897-1.050) | 0.741 | 0.180 | 0.942 (0.663-1.340) | |||
| EP1 (n) | 0.028 | 0.033 | 1.075 (1.008-1.146) | 0.331 | 0.112 | 1.115 (0.895-1.388) | 0.020 | 0.034 | 1.083 (1.012-1.157) |
| EP2 (c) | 0.019 | 0.058 | 0.873 (0.780-0.978) | 0.585 | 0.220 | 0.887 (0.576-1.365) | 0.111 | 0.068 | 0.897 (0.786-1.025) |
| EP2 (n) | 0.955 | 0.054 | 0.997 (0.897-1.108) | 0.245 | 0.385 | 0.639 (0.300-1.359) | |||
| EP3 (c) | 0.231 | 0.054 | 0.937 (0.842-1.042) | 0.729 | 0.200 | 0.933 (0.631-1.380) | |||
| EP3 (n) | 0.394 | 0.050 | 0.958 (0.869-1.057) | 0.870 | 0.167 | 1.028 (0.741-1.424) | |||
| EP4 (c) | 0.381 | 0.034 | 0.970 (0.907-1.038) | 0.842 | 0.118 | 0.977 (0.775-1.232) | |||
| pTstage | 0.289 | 0.116 | 0.884 (0.704-1.110) | 0.689 | 0.456 | 0.833 (0.341-2.037) | |||
| Grade | 0.715 | 0.133 | 1.050 (0.809-1.361) | 0.350 | 0.502 | 1.598 (0.598-4.271) | |||
Abbreviations: CSS=cancer-specific survival; (c)=cytoplasmic; (n)=nuclear; p = p-value, SE=standard error, HR=hazard ratio; significant values are shown in bold.