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. 2014 Jul 30;5(4):227–233. doi: 10.1016/j.shaw.2014.07.006

Table 4.

Comparison between hippuric acid levels and reported acute neurologic symptoms

Parameter Number of exposed workers Median of hippuric acid (mg/g creatinine) Interquartile range Range p
Headache
No 48 545 478 90–1280 < 0.001*
Yes 39 1145 824 220–2547
Dizziness
No 45 460 550 90–1875 < 0.001*
Yes 42 945 850 220–2547
Nausea
No 38 450 532 90–2420 < 0.001*
Yes 49 860 640 420–2547
Anorexia
No 55 790 520 90–1280 0.117
Yes 32 800 900 220–2547
Insomnia
No 39 790 530 90–1895 0.063
Yes 48 840 1000 160–2547
Loss of coordination
No 83 800 688 90–1895 0.974
Yes 4 840 860 160–2547
Muscle spasm
No 50 545 472 90–1895 < 0.001*
Yes 37 1145 812 220–2547

Hippuric acid levels in urine (mg/g creatinine) Airborne toluene levels (ppm).