TABLE 1.
BWHHS (n = 4286) |
MIDSPAN (n = 1477) |
Ten Towns (n = 1531) |
BRHS (n = 3945) |
EPIC (n = 7563) |
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Variables | n | Values | n | Values | n | Values | n | Values | n | Values |
Women, % | 4286 | 100 | 1477 | 54.91 | 1531 | 44.74 | 3945 | 0 | 7563 | 50.64 |
Age, y | 4284 | 68.88 ± 5.512 | 1477 | 45.39 ± 6.04 | 1531 | 15.06 ± 0.58 | 3945 | 68.74 ± 5.49 | 7563 | 59.50 ± 9.22 |
l-ascorbic acid, μmol/L | 3606 | 43.25 ± 28.04 | 1364 | 49.20 ± 25.27 | 1531 | 50.36 ± 23.92 | 3811 | 30.21 ± 27.55 | 7106 | 52.70 ± 20.40 |
SBP, mm Hg | 3964 | 147.13 ± 25.23 | 1464 | 127.53 ± 15.69 | 1527 | 120.82 ± 12.96 | 3942 | 142.78 ± 19.56 | 7552 | 136.08 ± 18.25 |
DBP, mm Hg | 3964 | 79.39 ± 11.66 | 1464 | 74.75 ± 11.17 | 1527 | 66.91 ± 7.34 | 3942 | 81.42 ± 12.80 | 7552 | 83.00 ± 11.16 |
WHR | 3946 | 0.82 ± 0.07 | 1462 | 0.84 ± 0.09 | 1528 | 0.76 ± 0.06 | 3918 | 0.95 ± 0.06 | 7556 | 0.86 ± 0.09 |
BMI, kg/m2 | 3957 | 27.62 ± 5.01 | 1467 | 26.19 ± 4.52 | 1525 | 20.93 ± 3.64 | 3926 | 26.88 ± 3.68 | 7563 | 26.48 ± 3.90 |
Cholesterol, mmol/L | 3851 | 6.64 ± 1.21 | 1452 | 5.29 ± 0.97 | 1523 | 4.22 ± 0.72 | 3927 | 6.31 ± 1.03 | 7329 | 6.18 ± 1.18 |
Glucose, mmol/L | 3829 | 6.06 ± 1.66 | 1454 | 5.35 ± 1.54 | 1500 | 5.09 ± 0.81 | 3925 | 5.56 ± 1.25 | 5842 | 4.51 ± 2.22 |
HDL cholesterol, mmol/L | 3845 | 1.66 ± 0.45 | 1279 | 1.42 ± 0.37 | 1523 | 1.45 ± 0.30 | 3813 | 1.15 ± 0.25 | 7026 | 1.40 ± 0.42 |
LDL cholesterol,3 mmol/L | 3762 | 4.14 ± 1.09 | 1276 | 3.20 ± 0.87 | 1523 | 2.32 ± 0.62 | 3832 | 3.90 ± 0.98 | 6957 | 3.65 ± 1.04 |
Triglycerides, mmol/L | 3851 | 1.87 ± 1.19 | 1448 | 1.60 ± 1.26 | 1523 | 1.01 ± 0.41 | 2805 | 2.03 ± 1.29 | 7329 | 1.89 ± 1.15 |
Prevalent hypertension4 | 2226 | 30.14 | 1477 | 13.20 | 1404 | 0.28 | 3942 | 53.53 | 6062 | 28.04 |
BRHS, British Regional Heart Study; BWHHS, British Women's Heart and Health Study; DBP, diastolic blood pressure; EPIC, European Prospective Investigation into Cancer; SBP, systolic blood pressure; WHR, waist-hip ratio.
Mean ± SD (all such values).
Derived by using Friedewald's equation (with the exclusion of individuals with triglyceride concentrations ≥4 mmol/L) (28).
Hypertension was defined as SBP ≥ 140 mm Hg and DBP ≥ 90 mm Hg.