. 2014 Nov 19;101(1):34–43. doi: 10.3945/ajcn.114.092262

TABLE 2.

Pearson's correlations (r) between fatty acids in fasting VLDL-TGs and NEFAs and selected characteristics of insulin resistance¹

	DNL_Meas	Liver fat, %	HOMA	AdipoIR
VLDL-TG fatty acid species (molar percentage)
16:1n–7	0.56^§	0.53^§	NS	0.56^§
18:1n–7	NS	NS	NS	NS
18:1n–9	NS	NS	NS	NS
14:0	NS	NS	NS	NS
16:0	NS	NS	NS	0.42*
18:0	NS	NS	0.50*	0.52*
VLDL-TG fatty acid ratios as candidate enzyme indicators
SCD1₍₁₆₎	0.50*	0.52*	NS	0.43*
SCD1₍₁₈₎	NS	NS	−0.45*	−0.42*
DNL_Index	NS	NS	0.52*	0.59 ^§
ELOVL6	NS	NS	0.42*	0.42*
Plasma NEFA species (molar percentage)
16:1n–7	0.60^§	NS	0.58^§	0.68^¶
18:1n–7	0.43*	0.57^§	0.52^§	0.53^§
18:1n–9	NS	NS	0.46*	0.45*
14:0	NS	NS	NS	NS
16:0	NS	NS	NS	NS
18:0	−0.48*	NS	−0.48*	−0.51*
Plasma NEFA ratios as candidate enzyme indicators (molar percentage)
SCD1₍₁₆₎	0.58^§	NS	0.55^§	0.60^§
SCD1₍₁₈₎	0.54^§	NS	0.55^§	0.56^§
DNL_Index	NS	NS	NS	NS
ELOVL6	−0.56^§	−0.50*	−0.44*	−0.57^§

DNL_Meas reflects VLDL-TG palmitate labeling using stable isotopes. AdipoIR is the product of fasting plasma insulin and NEFA concentrations. *P ≤ 0.05, ^§P ≤ 0.01, ^¶P ≤ 0.001. AdipoIR, adipose insulin resistance; DNL_Index, index of de novo lipogenesis (ratio of 16:0 to 18:2n–6 molar percentages in VLDL and plasma nonesterified fatty acids); DNL_Meas, isotopically measured de novo lipogenesis; ELOVL6, elongation of very-long-chain fatty acid protein 6 (ratio of 18:0 to 16:0); NEFA, nonesterified fatty acid; SCD1₍₁₆₎, ratio of 16:1n–7 to 16:0; SCD1₍₁₈₎, ratio of 18:1n–9 to 18:0; TG, triacylglycerol.