. 2014 Dec 3;14:130. doi: 10.1186/1471-2318-14-130

Table 1.

Characteristics of included studies

Author	Country	Setting	Age, mean (μ) ± SD	% females	Sample size	Follow-up	Outcome
Berry, 2008 [32]**	USA	1 LTC	μ: 89.0 (±6.1)	79%	184	8.5 years	Osteoporotic fractures
Broe, 2000 [35]	USA	1 LTC	μ: 88.0 (±6.2)	74%	252	6.6 years	Osteoporotic fractures
Chandler, 2000 [38]**	USA	47 NH	μ: 85.0 (±7.0)	100%	1427	18 months	Osteoporotic fractures
Chen, 2009 [22]**	Australia	NH, ICF	μ: 85.6	75%	1,894	4 years	Hip fracture
Chen, 2009 [22]**	Australia	Free dataset	μ: 85.6	75%	1,894	4 years	Hip fracture
Colon-Emeric, 2003 [40]	USA	NH	Fracture group μ: 81.96 ± 0.19	Fracture group 79%	13,516	1-2 years	Hip fracture
		MDS dataset		Fracture group 79%
				No fracture group: 68%
			No fracture group μ: 80.83 ± 0.05	No fracture group: 68%
Dobnig, 2007 [36]	Austria	NH	Ctrl μ: 83.8 (±6.2), Hip fracture μ: 83.6 (±6.3), Non-vertebral. Fracture μ 83.8 (±6.3)	100%	1,664	2 years	Hip* and Non- vertebral fracture
Dobnig, 2007 [36]	Austria	95 homes		100%	1,664	2 years	Hip* and Non- vertebral fracture
Huybrechts, 2011 [39]	Canada	NH	Atypical antipsychotics μ: 84.0 (±6.6)	Atypical antipsychotics: 58%	10,900	180 days	Femoral Fracture
		Data from BC Ministry of Health	Atypical antipsychotics μ: 84.0 (±6.6)	Atypical antipsychotics: 58%
		Data from BC Ministry of Health	Conventional antipsychotics μ: 83.0 (±6.8)	Conventional antipsychotics: 55%
Huybrechts, 2012 [33]	USA	NH	Conventional antipsychotics μ: 83.3	Conventional APMs: 69% atypical AMPS: 75%	83,959	180 days	Hip fracture
		MDS, Medicaid, OSCAR	Conventional antipsychotics μ: 83.3
		MDS, Medicaid, OSCAR	Atypical antipsychotics: 83.3
Lyles, 2008 [41]	USA	NH	Prior hip fractures μ: 83.3, Other fractures μ: 78.8	Prior hip fractures: 83% Other fractures: 80%	30,665	2 years	Osteoporotic fractures
		MDS and Medicare in North Carolina	Prior hip fractures μ: 83.3, Other fractures μ: 78.8	Prior hip fractures: 83% Other fractures: 80%
		MDS and Medicare in North Carolina	No prior fracture μ: 80.2	No prior fracture: 63%
Nakamura, 2010 [37]	Japan	140 NH	Women μ: 85.5 (±7.5), Men μ: 80.3 (±8.6)	76%	8,905	1 year	Hip fracture
Visenten, 1995 [34]**	Italy	1 NH	μ 81.5 (±8.0)	76%	197	3 years	Osteoporotic fractures

LTC = long term care; NH = nursing home; ICF = Intermediate Care Facility; MDS = Minimum Dataset; FREE = Fracture Risk Epidemiology in the Frail Elderly; BC = British Colombia.

*When results for 2 fracture sites were reported, we only included results of hip fractures.

**Study analysis restricted to subpopulation of long term care residents.