Figure 2. Effects of eIF3D knockdown on HCT116 cell proliferation and colony formation.
(A) The monolayer growth rates of HCT116 cells from three groups were determined by MTT assay. Statistical plots were made according to the results from three independent experiments. ***P<0.001, compared with Lv-shCon. (B) Down-regulation of eIF3D inhibited colony formation ability. Representative photographs of single colony and total colonies in plates were shown. (C) The average number of colonies in each plate was shown in the histogram. **P<0.01, compared with Lv-shCon.