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. 2014 Dec 3;7:64. doi: 10.1186/s12920-014-0064-y

Figure 3.

Figure 3

FLAGS genes are affected by rare variants predicted to be less deleterious than the variants affecting known disease-genes. (a) A boxplot distribution of proportion of variants with CADD score <10. The Y-axis plots the proportion of variants within each gene set having a Phred-scaled CADD score of <10. The proportion was calculated per individual gene. (b) A boxplot distribution of proportion of variants with CADD score >20. The Y-axis plots the proportion of variants within each gene set having a Phred-scaled CADD score of >20. The proportion was calculated per individual gene.