Table 2. Measures of Arterial Stiffness and Aβ Status in 81 Participants at Follow-up (July 2010 Through November 2012)a.
| Follow-up, Mean (SD) |
||||
|---|---|---|---|---|
| Characteristic | Aβ Positive (n = 61) |
Aβ Negative (n = 20) |
P Value for Unadjustedb | Model 1c per 1 SD, OR (95% CI) |
| Cardiovascular measures | ||||
|
| ||||
| baPWV, cm/s | 1888 (293) | 1610 (218) | <.001 | 4.06 (1.83-9.01) |
|
| ||||
| cfPWV, cm/s | 1618 (642) | 1393 (451) | .17 | 1.64 (0.76-3.58) |
|
| ||||
| hfPWV, cm/s | 1389 (266) | 1304 (297) | .25 | 1.49 (0.79-2.81) |
|
| ||||
| faPWV, cm/s | 1109 (196) | 989 (117) | .002 | 3.64 (1.46-9.08) |
|
| ||||
| Pulse rate, beats/min | 60 (12) | 60 (10) | .92 | 1.06 (0.53-1.88) |
|
| ||||
| SBP, mm Hg | 136 (17) | 129 (26) | .27 | 1.55 (0.84-2.85) |
|
| ||||
| DBP, mm Hg | 71 (11) | 68 (11) | .32 | 1.38 (0.78-2.45) |
|
| ||||
| PP, mm Hg | 66 (14) | 61 (17) | .25 | 1.45 (0.78-2.70) |
Abbreviations: Aβ, β-amyloid; baPWV, brachial-ankle pulse wave velocity; cfPWV, carotid-femoral pulse wave velocity; DBP, diastolic blood pressure; faPWV, femoral-ankle pulse wave velocity; hfPWV, heart-femoral pulse wave velocity; OR, odds ratio; PP, pulse pressure; SBP, systolic blood pressure.
a
Aβ status was determined using the iterative outlier approach (standardized uptake value ratio of >1.57).
b
Unadjusted P value from χ2 test.
c
Model 1 adjusted forage, sex, body mass index, and antihypertensive medications.