Table 1. Percent yield of hemi-aminal ether complex when number of molecular sieves (3 Å) and presence of Brønsted acid were varied. (Concentration of 2-PA: 35 mM, DPA: 42 mM, alcohol: 175 mM and Zn(ii): 35 mM in acetonitrile).
# of sieves | Brønsted acid | % Alcohol incorporation |
0 | N | 0 |
0 | Y | 40 |
2 | N | 0 |
2 | Y | 88 |
4 | N | 0 |
4 | Y | 90 |