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. 2014 Nov 3;111(49):17618–17623. doi: 10.1073/pnas.1413789111

Fig. 4.

Fig. 4.

CO as source of reductant for conversion of organic acids to alcohols by P. furiosus strain A/Codh. (A) Isobutanol formation (black squares) from isobutyrate (orange diamonds) in the presence of CO (purple diamonds) by cultures of strain A/Codh grown with maltose as the carbon source at 72 °C (n = 2; ±SD). (B) CO oxidation linked to organic acid reduction by P. furiosus strain A/Codh. The CODH complex oxidizes CO with the production of H2 and also reduces ferredoxin to provide low potential electrons to the AOR reaction. NADPH for the AdhA reaction is supplied by H2 oxidation by SHI.