Table 8.

Trials from Those Listed in Table 7 That Provide Information Regarding Mood and Fatigue Symptoms in the Trial Participants

Reference	Information about mood and fatigue
519	Individuals with mental illness or affective disorders were not allowed to participate in this trial.
384	The participants in this trial were prescreened for fatigue and mood, using validated questionnaires (Piper Fatigue Scale and General Health Questionnaire-30 [GHQ-30]), respectively. The sampling of participants was stratified according to severity of fatigue level; however, individuals with scores >45 on the GHQ-30 were excluded, due to an increased probability of depression (530,532,533).
388	This trial was conducted in individuals with primary hypothyroidism who were had evidence of depressive symptoms at baseline (GHQ administered on two occasions prior to randomization) (404,531).
524	Individuals with psychiatric disorders were not allowed to participate in this trial.
385	Individuals with untreated major depression were not allowed in this trial, but patients on stable doses of antidepressants were allowed if the depression treatment was unlikely to change.