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Detection of mitochondrial DNA (mtDNA) damage induced by cerebral ischemia assessed by quantitative polymerase chain reaction (QPCR) amplification after 30-minute and 100-minute middle cerebral artery occlusion (MCAO) or sham (S). Repair of mtDNA damage occurs after 30-minute (but not 100-minute) MCAO. (From Chen et al. 2003)
