Table 2.
Genotypic distribution of the 4-/5-length polymorphism of Per3 in bipolar disorder (BD) type I patients and controls based on sex
| Group | N | Genotype, n (%)
|
Allele, n (%)
|
χ2 | P | |||
|---|---|---|---|---|---|---|---|---|
| 4-/4- | 4-/5- | 5-/5- | 4- | 5- | ||||
| Male control | 184 | 73 (39.7) | 90 (48.9) | 21 (11.4) | 236 (0.64) | 132 (0.36) | 0.763 | 0.38 |
| Male BD | 152 | 60 (39.5) | 65 (42.8) | 27 (17.8) | 185 (0.61) | 119 (0.39) | ||
| Female control | 162 | 68 (41.9) | 73 (45.1) | 21 (12.9) | 209 (0.65) | 115 (0.35) | 4.532 | 0.03* |
| Female BD | 159 | 49 (30.8) | 81 (50.9) | 29 (18.3) | 179 (0.56) | 139 (0.44) | ||
Notes: 4-, 4-repeat allele; 5-, 5-repeat allele;
*
statistically significant.
Abbreviations: N, number of samples; n, number of genotypes and alleles.