Table 1.

Some factors to consider while managing patients with diabetes

Factors	Considerations
Age	Licensed indications (eg, dapagliflozin licensed for use in patients 18–75 years of age)
Weight	Weight-neutral or promotion of weight loss in overweight/obese patients
Pregnancy	Contraindications exist for most oral hypoglycemic agents
Renal/hepatic dysfunction	Metabolism of the drug and/or route of excretion
Ease of use	Frequency and timing of medication
Polypharmacy	This can lead to poor patient adherence12
Occupation	HGV drivers and the risk of hypoglycemia
Costs	Individual, national, or insurance costs can dictate medication choice
Side effects	Hypoglycemia, weight gain, gastrointestinal disturbance, edema, etc

Abbreviation: HGV, heavy goods vehicle.