Table S1.
Overall number of handling errors, in the second attempted use of the ELLIPTA® DPI or BREEZHALER™, following nonverbal demonstrative instruction
| Handling error | Error No. | ELLIPTA (n=150) n (%) [95% CI] | BREEZHALER (n=150) n (%) [95% CI] |
|---|---|---|---|
| At least one error | – | 3 (2.0) [0.4–5.7] | 49 (32.7) [25.2–40.8] |
| Turned the inhaler upside down after loading a dose | 1 | 0 (0.0) [0.0–2.4] | 0 (0.0) [0.0–2.4] |
| Shook the inhaler after loading a dose | 2 | 1 (0.7) [0.0–3.7] | 0 (0.0) [0.0–2.4] |
| Did not close the inhaler until hearing a click | 3 | N/A | 1 (0.7) [0.0–3.7] |
| Played with the side buttons | 4 | N/A | 11 (7.3) [3.7–12.7] |
| Could not insert a capsule into the inhaler capsule chamber without instructions | 5 | N/A | 0 (0.0) [0.0–2.4] |
| Did not hold the inhaler upright while pressing the side buttons* | 6 | N/A | 11 (7.3) [3.7–12.7] |
| Took inhaling posture without releasing the side buttons fully | 7 | N/A | 23 (15.3) [10.0–22.1] |
| Did not press the side buttons simultaneously until a “click” was heard before taking inhaling posture | 8 | N/A | 10 (6.7) [3.2–11.9] |
| Could not open the cover without instructions | 9 | 0 (0.0) [0.0–2.4] | N/A |
| Covered vent holes while taking the inhaling posture | 10 | 1 (0.7) [0.0–3.7] | N/A |
| Did not open cover until a “click” was heard before taking inhaling posture | 11 | 0 (0.0) [0.0–2.4] | N/A |
| Played with the cover | 12 | 1 (0.7) [0.0–3.7] | N/A |
Notes:
*
Allowable tilt ±45 degrees. Error numbers are identifiers assigned to each error for ease of reference. Errors 3–8 are applicable only to the BREEZHALER errors 9–12 are applicable only to the ELLIPTA DPI.
Abbreviations: CI, confidence interval; N/A, not applicable for this inhaler.