. 2014 Aug 21;23(24):3049–3064. doi: 10.1089/scd.2014.0157

Table 1.

Transcription Factor Expression Levels During 4h of Hyperosmotic Stress ± Enzyme Inhibition in mESC Monolayer Culture

4-h Inhibition	Oct4	Nanog	Rex1
Unstressed	1.00±0.00	1.00±0.00	1.00±0.00
Stress only (S)	0.52±0.03^a	0.65±0.07^a	0.63±0.06^a
PD98059 (MEK1)+S	0.93±0.09^b	2.57±0.50^a,b	1.20±0.05^b
U0126 (MEK1/2)+S	0.44±0.13^a	0.24±0.02^a,b	0.98±0.04^b
SB202190 (p38)+S	0.81±0.21	0.52±0.12^a	0.59±0.23^a
L-JNKi-1 (JNK)+S	0.21±0.04^a,b	1.08±0.11^b	0.47±0.04^a
LY294002 (PI3K)+S	0.92±0.12^b	0.55±0.10^a	0.36±0.14^a
AKTi+S	0.57±0.05^a	0.47±0.06^a	0.43±0.14^a

Values represent percent of unstressed expression.

^{^a}

Means statistically different from unstressed.

^{^b}

Means statistically different from “stress only,” n≥3, ANOVA and Student-Newman-Keuls post hoc tests, P<0.05.

JNK, c-Jun N-terminal kinase; PI3K, phosphoinositide 3-kinase.