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. Author manuscript; available in PMC: 2014 Dec 16.
Published in final edited form as: J Anesth. 2013 Apr 5;27(5):705–711. doi: 10.1007/s00540-013-1601-0

Table 3.

Notable therapeutic intervention and complications of patients with hereditary hemorrhagic telangiectasia undergoing general anesthesia

Perioperative blood transfusions
 Procedures for epistaxis
  • Septodermoplasty (7)

  • Nasal cauterization (3)

  • Miscellaneous procedures to nasal mucosa (2)

 Other procedures
  • Cardiac (5)

  • Liver transplant (2)

  • Major general surgeries (3)

  • Orthopedic surgery for septic arthritis (3)

Intensive care unit admission
 Procedures for epistaxis
  • Septodermoplasty in a patient with severe pulmonary hypertension for observation (2)

  • Septodermoplasty in a patient with severe pulmonary hypertension and 1-l blood loss

  • Nasal cauterization in a patient with severe pulmonary hypertension and hypoxic respiratory failure from right middle and lower lobe consolidation.

 Other procedures
  • Cardiac (6)

  • Liver transplant (4)

  • Major general surgeries (5)

  • Thoracic (2)

  • Interventional radiology (3)

  • Tracheostomy (1)

  • Neurosurgical (1)

Postoperative complications
 Epistasis following nonnasal procedures
  • Epistaxis noted postoperative day 6 following general surgery. Required transfusion of 11 units of packed red cells and coiling of a nasal arteriovenous malformation

  • Epistaxis noted postoperative day 6 following mitral valve repair. Treated with pressure and topical phenylephrine

 Neurological deficits
  • Self-limited expressive aphasia manifested 3 days after coiling of complex left cortical pial arteriovenous fistula

  • A coil deployed to a pulmonary arteriovenous malformation migrated to the main middle cerebral artery. It was immediately retrieved by a snare and the patient treated with heparin and tissue plasminogen activator. Complicated by transient hemiparesis

 Other
  • Pulmonary infarction secondary to coiling of pulmonary arteriovenous malformation