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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Med Primatol. 2014 Aug 1;43(6):468–476. doi: 10.1111/jmp.12138

Table 1.

Nodular astrocytosis in SIV-infected rhesus macaques.

Case1 Sex Age SIV variant
(inoculation
route)		 Days post
SIV (first
inoculation)		 SAIDS Location of
nodular
astrocytosis		 Neurologic
signs2 		Diameter of
representative
nodule (μm)
1 M adult SIVmac239g46
(iv)		 624 + Cerebral cortex
(frontal,
temporal,
occipital),
cerebellum,
brainstem		 Present 100-200
2 F 8 yr SIVmac239Δnef
(iv, ip)		 2,080 + Cerebral
cortex,
cerebellum		 None
noted		 300-800
3 M 4 yr SIVmac239 (iv) 639 + Cerebral cortex None
noted		 100-200
4 F 10 yr SIVmac239Δnef
(iv), SIVmac251
(intravaginal)		 1,777 − Globus pallidus None
noted		 200
5 F 5 yr SIVmac251
(intravaginal)		 338 + Frontal cortex,
thalamus,
cerebellum		 Advanced 100-200
1

1,206 total cases (0.4% incidence)

2

including head tilt, ataxia, falling off of perch, etc.