Table 8. Comparison of CS LN Involvement From 2004-2010 to SSF2: Size of Metastasis in Regional Lymph Nodesa in 2010.
| AJCC 6th Edition | AJCC 7th Edition | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CS LN | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010a | SSF2b | 2010 |
| N0: No known regional lymph node involvement | 15215 (90.9) | 15195 (91.3) | 15155 (91.5) | 15618 (91.6) | 15688 (92.0) | 15821 (92.4) | 16092 (92.8%) | No lymph nodes involved Code: 000 | 15 766 (90.9%) |
| N1: Single node, <2 cm | 362 (2.2%) | 388 (2.3%) | 419 (2.5%) | 408 (2.4%) | 429 (2.5%) | 397 (2.3%) | 253 (1.5%) | <2 cm Codes: 001-200, 990-992 | 280 (1.6%) |
| N2: Single node, 2-5 cm, or Multiple nodes | 158 (0.9%) | 162 (1.0%) | 200 (1.2%) | 239 (1.4%) | 223 (1.3%) | 224 (1.3%) | 400 (2.3%) | 2-5 cm Codes: 201-500, 993-995 | 18 (0.1%) |
| N3: One or more nodes, >5 cm | 10 (0.1%) | 19 (0.1%) | 16 (0.1%) | 19 (0.1%) | 12 (0.1%) | 19 (0.1%) | 8 (0.1%) | >5 cm 501-980, 996-997 | 4 (0.0%) |
| NX: Unknown regional lymph node involvement | 993 (5.9%) | 879 (5.3%) | 781 (4.7%) | 771 (4.5%) | 703 (4.1%) | 655 (3.8%) | 585 (3.4%) | Unknown 999 | 1270c(7.3%) |
| TOTAL | 16738 (100%) | 16643 (100%) | 16571 (100%) | 17055 (100%) | 17055 (100%) | 17116 (100%) | 17338 (100%) | 17 338 (100%) | |
Abbreviations: AJCC, American Joint Committee on Cancer; cm, centimeter; CS, Collaborative Staging; LN, lymph nodes; SSF, site-specific factor.
a
The AJCC 6th edition was applied to 2010 cases for the purposes of this analysis. In Surveillance, Epidemiology, and End Results (SEER) Program public release files, 2010 cases are staged according to the AJCC 7th edition.
b
SSF2 is based on the size of the largest metastasis in the Regional Lymph Nodes.
c
This includes 12 cases that were coded as SSF2 = 00 (no lymph node involvement), despite having a CS LN code that indicated involvement.