Table 1.
Videomicroscopy (OPS imaging, SDF imaging) | Laser Doppler perfusion imaging | Laser speckle contrast imaging | |
---|---|---|---|
Variables measured | Vessel diameter, vessel density, RBC velocity, heterogeneity of perfusion | RBC mean velocity, RBC concentration | RBC mean velocity, RBC concentration |
Contact | Yes | No | No |
Measuring depth | ~500 μm | ~1–1.5 mm | ~300 μm |
Pros | Direct visualization of microcirculation | Non-contact | Non-contact, fast |
Cons | Motion artifacts, pressure artifacts, time consuming analysis | Motion artifacts, long measurement time, relative measurements | Motion artifacts, relative measurements |
Abbreviations: OPS, orthogonal polarization spectral; SDF, sidestream dark-field; RBC, red blood cells.