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. 2014 Dec 9;7:445–452. doi: 10.2147/MDER.S51426

Table 1.

Overview of microcirculation imaging methods

Videomicroscopy (OPS imaging, SDF imaging) Laser Doppler perfusion imaging Laser speckle contrast imaging
Variables measured Vessel diameter, vessel density, RBC velocity, heterogeneity of perfusion RBC mean velocity, RBC concentration RBC mean velocity, RBC concentration
Contact Yes No No
Measuring depth ~500 μm ~1–1.5 mm ~300 μm
Pros Direct visualization of microcirculation Non-contact Non-contact, fast
Cons Motion artifacts, pressure artifacts, time consuming analysis Motion artifacts, long measurement time, relative measurements Motion artifacts, relative measurements

Abbreviations: OPS, orthogonal polarization spectral; SDF, sidestream dark-field; RBC, red blood cells.