Table 2. Known Wnt target genes that were downregulated and annotated ChIP-seq peaks.
| Wnt target gene | Fold change: 2 h, 9 h | 2 h peak distance from TSS (bp) | 9 h peak distance from TSS (bp) |
|---|---|---|---|
| ASCL2 | -2.4, -3.0 | - | - |
| AXIN2 | -1.7, -2.8 | 483, 4234, 127 488 | -122 214, -31 782, -4127, 550, 4401, 7366, 64 102, 127 472, 167 808 |
| BMP4 | -1.6, -2.6 | -215 569, -152 132, -145 446 | -42 955 |
| CDX2 | -1.9, -2.6 | 2396, 3221 | 2362, 3257 |
| DKK1 | -5.5, -6.7 | 39 631, 138 559 | - |
| FZD7 | -2.4, -2.6 | -40 047, 34 670, 35 777 | 34 525, 93 752 |
| JAG1 | -1.4, -1.9 | -32154 | -45 733, -34 836 |
| LGR5 | N/A, -1.8 | 931 | 990, 29 670, 54 199 |
| MYC | -2.4, -3.1 | 7022 | -104 616 |
| PITX2 | -1.5, -1.7 | -284 838, -219 399, -183 246 | -422 541, -419 957, -200 616 |
| PPIF | -1.4, -1.7 | - | - |
| SGK1 | -2.2, -2.5 | 12 239 | 16 390, 17 705, 31 467 |
| SOX4 | -2.4, -3.1 | -208 433, -31 951, 11 965 | -527 001, -174 480, -90 544, -37 651, 1316 |
| SOX9 | -1.6, -1.9 | -160 304 | 746 421, -602 259, -336 893, -258 580, -199 838, -11 372 |
| SP5 | -2.2, -2.9 | -176 | -162 |
| TBX3 | -1.8, -1.8 | -693 657, -503 686, -97 493, -84 395, 27 773, 97 991 | -315 734, -283 946, -138 493, -137 130 |
| TCF4 | -1.3, -2.2 | 31 461, 134 605, 159 291 | 3716, 24 346, 31 485 |
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