Table 2. Alternatively spliced GYNNGY sites showing tissue-dependent regulation.
| Human | Mouse | |||||
|---|---|---|---|---|---|---|
| CDS | UTR | Total | CDS | UTR | Total | |
| Total sitesa | 510 | 111 | 621 | 652 | 86 | 738 |
| Regulatedb | 219 | 58 | 277 | 41 | 9 | 50 |
| Strongly regulated (%)c | 75 (14.71) | 43 (38.74) | 118 (19.00) | 15 (2.30) | 6 (6.98) | 21 (2.85) |
aOnly sites that had expression in at least two tissues (≥10 reads in each tissue) are considered, because at least two tissues are needed for chi-squared test.
bThe sites that showed tissue-specific regulation (FDR ≤ 0.01).
cThe regulated sites that had ΔUMS ≥ 0.25. The proportion of strongly regulated GYNNGYs is significantly higher in UTRs than in CDS (chi-square test, P = 1.094 x 10-8 for human and Fisher's exact test, P = 0.02689 for mouse).