Skip to main content
. Author manuscript; available in PMC: 2014 Dec 16.
Published in final edited form as: Clin Pharmacol Ther. 2014 Sep 4;96(6):672–683. doi: 10.1038/clpt.2014.174

Figure 5.

Figure 5

SS-20 protects kidney mitochondria during ischemia. Rats were treated with SS-20 or saline 30 min before bilateral occlusion of renal blood flow for 45 min. Electron microscopic images were taken from kidney sections 5 min after onset of reperfusion. Left panel: representative section from sham animals shows elongated mitochondria with dense cristae membranes. Middle panel: saline-treated ischemic kidneys show matrix swelling and loss of cristae membranes. Right panel: SS-20-treated ischemic kidneys show normal mitochondrial structure with preserved cristae architecture. All images are presented at ×80,000 original magnification.