Table 4. The minimum inhibitory concentrations (MICs) of various antibiotics for C. glutamicum strains.
| Antibiotics | MIC (µg ml−1) | ||
| WT(pXMJ19) | Δmca(pXMJ19) | Δmca(pXMJ19-mca) | |
| Macrolide | |||
| Erythromycin | 25.00 | 25.00 | 25.00 |
| Lincomycin | 62.50 | 62.50 | 62.50 |
| Rifamycin S | 12.50 | 3.125 | 6.25–3.125 |
| Spectinomycin | 128.00 | 128.00 | 128.00 |
| β-Lactam | |||
| Penicillin | >350.00 | >350.00 | >350.00 |
| Glycopeptide | |||
| Vancomycin | 32.00 | 16.00–8.00 | 32.00–16.00 |
| Aminoglycoside | |||
| Streptomycin | 1.25 | 0.3125–0.156 | 0.625 |
| Neomycin | 7.50 | 3.75 | 7.50 |
| Gentamycin | 5.00 | 5.00 | 5.00 |
| Quinolone | |||
| Ciprofloxacin | 1.562 | 0.391 | 1.562–0.781 |
| Tetracycline | |||
| Tetracycline | 3.125 | 0.781 | 1.562 |
**P≤0.01 versus wild type for the mutants.
a
The values are mean±SD for three independent determinations.