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. 2014 Dec 16;9(12):e114086. doi: 10.1371/journal.pone.0114086

Table 4. A2A and NR2B receptor antagonist combinations tested either alone or in combination as add-on therapy to L-Dopa in 6-OHDA-lesioned rats.

A2A receptor antagonist drugs NR2B receptor antagonist drugs
Sch-58261 0.3 mg/kg (ip) Co-101244 1 mg/kg (ip)
Preladenant 0.03 mg/kg (ip) Radiprodil 0.3 mg/kg (ip)
Preladenant 0.03 mg/kg (ip) Merck 22 1 mg/kg (ip)
Tozadenant 30 mg/kg (po) Radiprodil 3 mg/kg (po)