Table 2.
Severity classification and duration of illness of dengue-infected non-ICU (controls) and ICU (cases) patients
| Variables | Den-infected non-ICU controls (n = 108) | %/(IQR) | Den-infected ICU cases (n = 27) | %/(IQR) | COR | P-value | 95% CI | ACOR* | P-value | 95% CI |
|---|---|---|---|---|---|---|---|---|---|---|
| WHO 1997 (Presentation) | ||||||||||
| DHF/DSS | 14 | 13 | 5 | 19 | 1.5 | 0.469 | 0.50–4.4 | 1.8 | 0.34 | 0.54–6.08 |
| WHO 2009 (Presentation) | ||||||||||
| Severe dengue | 7 | 6.5 | 14 | 52 | 10.3 | <0.001 | 3.70–28.84 | 8.79 | <0.001 | 2.65–29.16 |
| WHO 1997 (Outcome) | ||||||||||
| DHF/DSS | 24 | 22 | 18 | 67 | 7.65 | <0.001 | 2.74–21.35 | 2.99 | 0.025 | 1.15–7.78 |
| WHO 2009 (Outcome) | ||||||||||
| Severe dengue | 11 | 10 | 24 | 89 | 73.1 | <0.001 | 9.82–543.96 | 116.4 | <0.001 | 8.79–1541 |
| Median DPP to DHF/DSS | 3 | (2.3–3.8) | 4 | (3–5) | 1.79 | 0.206 | 0.73–4.43 | 3.08 | 0.677 | 0.02–608 |
| Median DPP to Severe dengue | 2.5 | (1.8–3.3) | 3 | (3–5) | ||||||
| Median LOS in hospital | 4 | (3–5) | 8 | (6–13.5) | 1.73 | <0.001 | 1.30–2.32 | 1.76 | 0.001 | 1.28–2.43 |
| Median DPF on ICU requirement | N.A | 6 | (4–7.5) | |||||||
| Median DPP on ICU requirement | N.A | 3 | (2–4.5) | |||||||
| Median LOS in ICU | N.A | 3 | (2–4) | |||||||
| Death | 0 | 0 | 7 | 26 | ||||||
| Median DPF to death | N.A | 7 | (7–15.5) | |||||||
| Median DPP to Death | N.A | 3 | (2.5–7.5) |
DPF- Days Post Fever; DPP- Days Post Presentation; LOS- Length of Stay; COR- Conditional Odds Ratio; IQR- Interquartile range.
*Adjusted Conditional Odds Ratio (ACOR) was obtained from a multivariate conditional logistic regression with test variables being adjusted by age and diabetes mellitus.
Data in bold are risk factors significantly associated with ICU requirement.