Table 3. Relationship between surfactant proteins and RAGE levels and general, clinical, pulmonary function and cardiopulmonary exercise data in the heart failure population.
Immature SPB | Mature SPB | SPA | SPD | RAGE | ||
AGE (yrs) | r value | 0.265 | 0.013 | 0.256 | 0.152 | 0.066 |
p value | 0.012 | NS | 0.015 | NS | NS | |
BMI (Kg/m2) | r value | –0.156 | 0.144 | –0.052 | –0.203 | –0.285 |
p value | NS | NS | NS | NS | <0.01 | |
DLCO (%pred) | r value | –0.591 | –0.088 | –0.429 | –0.393 | –0.245 |
p value | <0.01 | NS | <0.01 | <0.01 | 0.023 | |
pVO2 (mL/Kg) | r value | –0.426 | –0.012 | –0.408 | –0.292 | –0.265 |
p value | <0.01 | NS | <0.01 | <0.01 | 0.01 | |
VE/VCO2 slope | r value | 0.363 | –0.037 | 0.455 | 0.333 | 0.406 |
p value | <0.01 | NS | <0.01 | <0.01 | <0.01 | |
BNP (pg/mL) | r value | 0.367 | –0.008 | 0.502 | 0.412 | 0.490 |
p value | <0.01 | NS | <0.01 | <0.01 | <0.01 | |
Hb (g/dL) | r value | –0.088 | 0.067 | –0.170 | –0.069 | –0.285 |
p value | NS | NS | NS | NS | <0.01 | |
Creatinine (mg/dL) | r value | 0.268 | –0.253 | 0.245 | 0.184 | 0.367 |
p value | <0.01 | 0.016 | 0.02 | NS | <0.01 |