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. 2014 Dec 16;9(12):e114617. doi: 10.1371/journal.pone.0114617

Table 3. Groups of enriched gene ontology (GO) terms for differentially expressed genes common to both trisomy 2 and tertiary trisomy 2.

Category GO term no. Description (Ontologya) p-value FDRb
Group I GO:0009814 defense response, incompatible interaction (P) 1.4E-25 8.8E-24
GO:0006955 immune response (P) 5.1E-10 8.6E-09
GO:0051704 multi-organism process (P) 1.1E-06 1.0E-05
GO:0006950 response to stress (P) 2.1E-05 1.6E-04
GO:0050896 response to stimulus (P) 9.9E-04 5.7E-03
GO:0016788 hydrolase activity, acting on ester bonds (F) 4.4E-03 4.5E-02
Group II GO:0050896 response to stimulus (P) 1.8E-25 2.0E-23
GO:0042221 response to chemical stimulus (P) 3.3E-24 3.0E-22
GO:0009725 response to hormone stimulus (P) 7.0E-17 3.5E-15
GO:0006950 response to stress (P) 2.5E-15 1.0E-13
GO:0006869 lipid transport (P) 5.8E-11 1.9E-09
GO:0006952 defense response (P) 8.6E-07 1.6E-05
GO:0019748 secondary metabolic process (P) 5.9E-06 1.0E-04
GO:0040007 growth (P) 5.5E-05 9.0E-04
GO:0006955 immune response (P) 1.4E-04 2.1E-03
GO:0003824 catalytic activity (F) 6.6E-04 3.1E-02
GO:0003700 transcription factor activity (F) 2.1E-03 4.3E-02
Group III GO:0007165 signal transduction (P) 3.3E-05 1.3E-03
GO:0006350 transcription (F) 3.4E-03 3.4E-02
GO:0005488 binding (F) 2.1E-03 3.8E-02
Group IV GO:0009733 response to auxin stimulus (P) 1.1E-08 3.5E-06
GO:0042221 response to chemical stimulus (P) 2.1E-04 2.5E-02
GO:0009725 response to hormone stimulus (P) 5.3E-04 3.3E-02
GO:0005975 carbohydrate metabolic process (P) 9.0E-04 4.6E-02

The gene ontology was analyzed by use of AgriGO [33].

a

Biological process (P); molecular function (F).

b

Chi-square statistical test; FDR, false discovery rate.