Table 3. Groups of enriched gene ontology (GO) terms for differentially expressed genes common to both trisomy 2 and tertiary trisomy 2.
Category | GO term no. | Description (Ontologya) | p-value | FDRb |
Group I | GO:0009814 | defense response, incompatible interaction (P) | 1.4E-25 | 8.8E-24 |
GO:0006955 | immune response (P) | 5.1E-10 | 8.6E-09 | |
GO:0051704 | multi-organism process (P) | 1.1E-06 | 1.0E-05 | |
GO:0006950 | response to stress (P) | 2.1E-05 | 1.6E-04 | |
GO:0050896 | response to stimulus (P) | 9.9E-04 | 5.7E-03 | |
GO:0016788 | hydrolase activity, acting on ester bonds (F) | 4.4E-03 | 4.5E-02 | |
Group II | GO:0050896 | response to stimulus (P) | 1.8E-25 | 2.0E-23 |
GO:0042221 | response to chemical stimulus (P) | 3.3E-24 | 3.0E-22 | |
GO:0009725 | response to hormone stimulus (P) | 7.0E-17 | 3.5E-15 | |
GO:0006950 | response to stress (P) | 2.5E-15 | 1.0E-13 | |
GO:0006869 | lipid transport (P) | 5.8E-11 | 1.9E-09 | |
GO:0006952 | defense response (P) | 8.6E-07 | 1.6E-05 | |
GO:0019748 | secondary metabolic process (P) | 5.9E-06 | 1.0E-04 | |
GO:0040007 | growth (P) | 5.5E-05 | 9.0E-04 | |
GO:0006955 | immune response (P) | 1.4E-04 | 2.1E-03 | |
GO:0003824 | catalytic activity (F) | 6.6E-04 | 3.1E-02 | |
GO:0003700 | transcription factor activity (F) | 2.1E-03 | 4.3E-02 | |
Group III | GO:0007165 | signal transduction (P) | 3.3E-05 | 1.3E-03 |
GO:0006350 | transcription (F) | 3.4E-03 | 3.4E-02 | |
GO:0005488 | binding (F) | 2.1E-03 | 3.8E-02 | |
Group IV | GO:0009733 | response to auxin stimulus (P) | 1.1E-08 | 3.5E-06 |
GO:0042221 | response to chemical stimulus (P) | 2.1E-04 | 2.5E-02 | |
GO:0009725 | response to hormone stimulus (P) | 5.3E-04 | 3.3E-02 | |
GO:0005975 | carbohydrate metabolic process (P) | 9.0E-04 | 4.6E-02 |
The gene ontology was analyzed by use of AgriGO [33].
Biological process (P); molecular function (F).
Chi-square statistical test; FDR, false discovery rate.